N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide CAS 341966-65-2
| CAS No. | 341966-65-2 |
| Molecular Formula | C21H16Cl2FN3O4 |
| Molecular Weight | 464.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 464.27 g/mol gives N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide (CAS 341966-65-2), molecular formula C21H16Cl2FN3O4 and molecular weight 464.27 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 464.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H16Cl2FN3O4 |
| Molecular Weight | 464.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- N-[(1E)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide (CAS 341966-68-5)
- Etravirine Iimpurity 8 (CAS CATO-C4X-13568)
- 5,6-Dimethoxy-8-nitroquinoline (CAS 5333-02-8)
- 2-(4-Bromophenyl)-6-methyl-1-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one (CAS 1024400-40-5)
- 4-(Aziridin-1-yl)-6-chloropyrimidine (CAS 14673-04-2)
- methyl 3-[(2-amino-1,3-thiazol-5-yl)methyl]benzoate hydrochloride (CAS 1235440-80-8)
- 4-(Trifluoromethoxy)pyrrolidine-2-carboxylic acid (CAS 1301738-64-6)
- 2,4-Dibromo-5-(chlorosulfonyl)benzoic acid (CAS 1432679-77-0)
- 4-ethylmorpholine-2-carbonitrile (CAS 1354950-43-8)
- 9-Methyl-7,8,9,10-tetrahydropyrido[2',3':4,5]thieno[2,3-b][1,6]naphthyridine-2,4-diol (CAS 290299-91-1)
- 1,4-Dibromobutene (CAS 30794-77-5)
- ethyl 5-(chloromethyl)-1,2,4-oxadiazole-3-carboxylate (CAS 1009620-97-6)
- 1-Bromo-4-(bromoethynyl)benzene (CAS 934-94-1)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
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