2-(4-Bromophenyl)-6-methyl-1-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one CAS 1024400-40-5
| CAS No. | 1024400-40-5 |
| Molecular Formula | C22H17BrF3NO2 |
| Molecular Weight | 464.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(4-Bromophenyl)-6-methyl-1-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one (CAS 1024400-40-5), a certified reference material (molecular formula C22H17BrF3NO2, MW 464.28 g/mol) for analytical method development and quality control.
2-(4-Bromophenyl)-6-methyl-1-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one (C22H17BrF3NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-(4-Bromophenyl)-6-methyl-1-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17BrF3NO2 |
| Molecular Weight | 464.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- Etravirine Iimpurity 8 (CAS CATO-C4X-13568)
- 2-[3-(2-Chloro-6-fluorophenyl)-4-methyl-1,2-oxazol-5-yl]-7-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 860611-27-4)
- N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide (CAS 341966-65-2)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione (CAS 303151-59-9)
- tert-Butyl 3-(bromomethyl)-1H-pyrazole-1-carboxylate (CAS 186551-69-9)
- 5-Bromo-2-(methoxymethyl)pyridine (CAS 1000787-43-8)
- 2-(4-Fluorobenzyl)butanoic acid (CAS 1017146-79-0)
- 5-chlorothiophen-3-amine (CAS 123403-75-8)
- 3-(4-Fluorophenoxy)propan-1-amine hydrochloride (CAS 148941-98-4)
- N-(Thiazol-2-ylmethyl)formamide (CAS 93714-84-2)
- 4-chloro-3-iodo-1H-pyrazolo[4,3-c]pyridine (CAS 1186647-69-7)
- 3-Acetyl-4-methylphenethyl indolizine-6-carboxylate (CAS 59603-70-2)
- Tert-butyl (3-methylbenzyl)glycinate (CAS 1178928-42-1)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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