Granisetron EP Impurity G CAS 34252-44-3
| CAS No. | 34252-44-3 |
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Granisetron EP Impurity G.
CATO supplies Granisetron EP Impurity G (CAS 34252-44-3), a pharmacopoeial impurity reference standard (molecular formula C9H8N2O2, MW 176.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Granisetron EP Impurity G is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 176.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Granisetron EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 2 |
Related Granisetron Standards
- Granisetron EP Impurity D (CAS 50890-83-0)
- Granisetron EP Impurity H (CAS 4498-67-3)
- Granisetron Impurity 12 (CAS 106649-02-9)
- Granisetron EP Impurity E (CAS 76272-56-5)
- Granisetron Impurity 10 (CAS 123704-99-4)
- Granisetron Impurity 11(Mixture of Z and E Isomers) (CAS 123704-98-3)
- Granisetron Impurity 27 (CAS 10604-20-3)
- Granisetron Impurity 24 (CAS CATO-C4X-197024)
Recommended Standards
- Ozagrel Impurity 26 （predominantly trans） (CAS 23359-08-2)
- Zonisamide Impurity 14 (CAS 23008-68-6)
- Regadenoson Impurity 36 (CAS 871301-32-5)
- Rizatriptan Impurity 13 (CAS 91192-27-7)
- Vildagliptin Impurity 41 (CAS 1616662-84-0)
- Terbutaline Impurity 53 (CAS 51863-60-6)
- Tizanidine Nitroso Impurity 15 (CAS CATO-C4X-144515)
- Cefmetazole Impurity 16 (CAS CATO-C4X-150716)
- 2-(6-(Trifluoromethyl)-1H-indazol-3-yl)ethanamine (CAS 1360946-75-3)
- 2-[(4-Chlorophenyl)sulfanyl]-N-(4-cyclohexylphenyl)acetamide (CAS 212074-97-0)
- 2-Cyano-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)pyridine (CAS 1449117-69-4)
- (D-Phe12,Nle21·3?,α-Me-Leu3?)-CRF (12-41) (human, rat) (CAS 150646-45-0)
- rel-(+)-(1S,2R)-2',3'-Dihydrospiro[cyclopropane-1,1'-inden]-2-amine (CAS 2102609-48-1)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com