Sunitinib Impurity 31 CAS 342641-94-5
| CAS No. | 342641-94-5 |
| Molecular Formula | C22H27FN4O2 |
| Molecular Weight | 398.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Sunitinib Impurity 31 (CAS 342641-94-5) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27FN4O2 and a molecular weight of 398.47 g/mol.
Sunitinib Impurity 31 (C22H27FN4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sunitinib Impurity 31 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27FN4O2 |
| Molecular Weight | 398.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Sunitinib Standards
- Sunitinib Impurity 28 (CAS CATO-C4X-133328)
- Sunitinib Impurity 29 (CAS 2417674-16-7)
- Sunitinib Impurity 30 (CAS CATO-C4X-133330)
- Sunitinib (CAS 557795-19-4)
- (E)-Sunitinib (CAS 1691223-83-2)
- Sunitinib impurity 69 (CAS CATO-C4X-133369)
- Sunitinib-d4 (CAS 1126721-79-6)
- Sunitinib Impurity 65 (CAS CATO-C4X-133365)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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