Dopamine Impurity 92 CAS 344791-89-5
| CAS No. | 344791-89-5 |
| Molecular Formula | C10H13ClO |
| Molecular Weight | 184.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dopamine Impurity 92.
CATO supplies Dopamine Impurity 92 (CAS 344791-89-5), a pharmacopoeial impurity reference standard (molecular formula C10H13ClO, MW 184.66 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Dopamine Impurity 92 (C10H13ClO) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13ClO |
| Molecular Weight | 184.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ＞95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Dopamine Standards
- Dopamine Impurity 64 (CAS CATO-C4X-190864)
- Dopamine Impurity 67 (CAS CATO-C4X-190867)
- Dopamine Impurity 14 (CAS 21581-37-3)
- Dopamine Impurity 29 (CAS 15806-29-8)
- Dopamine Impurity 31 (CAS 3213-28-3)
- Dopamine Impurity 75 (CAS 32602-66-7)
- Dopamine EP Impurity C (CAS 120-20-7)
- Dopamine Impurity 85 (CAS 763024-20-0)
Recommended Standards
- Dapoxetine Impurity 53 (CAS 22422-27-1)
- Latanoprost Impurity 20 (CAS 881647-78-5)
- Metoprolol Impurity 20 (CAS 18995-35-2)
- Latanoprost Impurity 21 (CAS 153475-15-1)
- Goserelin Impurity 18 (CAS CATO-C4X-192018)
- Paroxetine Impurity 22 (CAS 127017-78-1)
- Testosterone Impurity 29 (CAS CATO-C4X-243229)
- 1H-Pyrazolo[4,3-b]pyridin-7(4H)-one (CAS 94220-42-5)
- 6-Iodobenzo[d]oxazol-2-amine (CAS 1804102-68-8)
- 5-(TERT-BUTYLDIMETHYLSILYLOXY)-4,4-DIMETHYL-3-OXOPENTANENITRILE (CAS 1229454-44-7)
- 2,5-Dibromo-1-(difluoromethyl)-3-fluorobenzene (CAS 1807056-00-3)
- n1-(2,6-Difluorobenzyl)-n2,n2-dimethylethane-1,2-diamine (CAS 953891-59-3)
- (3S)-6-(trifluoromethyl)-2,3-dihydro-1-benzofuran-3-amine (CAS 1272724-36-3)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com