Latanoprost Impurity 20 CAS 881647-78-5
| CAS No. | 881647-78-5 |
| Molecular Formula | C10H13ClO |
| Molecular Weight | 184.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Latanoprost Impurity 20 (CAS 881647-78-5, C10H13ClO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H13ClO, Latanoprost Impurity 20 contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 184.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Latanoprost Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13ClO |
| Molecular Weight | 184.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
Related Latanoprost Standards
- Latanoprost Impurity 21 (CAS 153475-15-1)
- Latanoprost Impurity 23 (CAS 124988-64-3)
- Latanoprost Impurity 12 (CAS 125637-06-1)
- Latanoprost Impurity 22 (CAS 141036-66-0)
- Latanoprost Lactone Diol (CAS 145667-75-0)
- Latanoprost Impurity 6 (CAS 352276-28-9)
- Latanoprost EP Impurity D (CAS 2088449-88-9)
- Latanoprost Impurity 13 (CAS 2764760-31-6)
Recommended Standards
- Dopamine Impurity 92 (CAS 344791-89-5)
- Dapoxetine Impurity 53 (CAS 22422-27-1)
- 4-Chloro-2-Isopropyl-5-Methylphenol (CAS 89-68-9)
- Metoprolol Impurity 20 (CAS 18995-35-2)
- Labetalol Impurity 32 (CAS 345933-79-1)
- Paclitaxel EP Impurity R (CAS 158948-96-0)
- Indobufen Impurity 37 (CAS 858847-40-2)
- 2-Propenoic acid, homopolymer, zinc salt (CAS 25916-47-6)
- Ethyl 5-amino-1-(pyridin-4-yl)-1H-pyrazole-4-carboxylate (CAS 38965-48-9)
- Prilocaine Impurity 63 (CAS CATO-C4X-193463)
- TERT-BUTYL CYCLOBUTYLIDENECARBAZATE (CAS 158001-20-8)
- tert-Butyl (3-bromo-6,7-dihydro-5H-cyclopenta[b]pyridin-4-yl)carbamate (CAS 2861287-00-3)
- γ-Valprolactone (CAS 40923-58-8)
- HIV (gp120) Antigenic Peptide (H-2982.0500) (CAS 198636-94-1)
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