2-Hydroxy-6-trifluoromethylpyridine CAS 34486-06-1
| CAS No. | 34486-06-1 |
| Molecular Formula | C6H4F3NO |
| Molecular Weight | 163.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Hydroxy-6-trifluoromethylpyridine (C6H4F3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 163.10 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Hydroxy-6-trifluoromethylpyridine (CAS 34486-06-1), molecular formula C6H4F3NO and molecular weight 163.10 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Hydroxy-6-trifluoromethylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4F3NO |
| Molecular Weight | 163.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 4-Hydroxy-2-(trifluoromethyl)pyridine (CAS 170886-13-2)
- 3-Hydroxy-5-(trifluoromethyl)pyridine (CAS 186593-14-6)
- 2-Hydroxy-5-(Trifluoromethyl)Pyridine (CAS 33252-63-0)
- 9-Hydroxy-4H-pyrimido[1,6-a]pyrimidin-4-one (CAS 123420-39-3)
- 4-Hydroxy-5H-cyclohepta[d]isoxazol-5-one (CAS 178315-30-5)
- 4-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione (CAS 41709-87-9)
- 4-Hydroxy-2H-pyrano[3,2-b]pyridin-2-one (CAS 55502-23-3)
- (Z)-4-Hydroxy-4-(pyridin-2-yl)but-3-en-2-one (CAS 1031694-63-9)
Recommended Standards
- 6-Trifluoromethyl-pyrazin-2-ylamine (CAS 69816-35-9)
- 6-(Trifluoromethyl)pyridin-3-ol (CAS 216766-12-0)
- Diethyl Cyanophosphonate (CAS 2942-58-7)
- 5-Amino-2-(trifluoromethyl)pyrimidine (CAS 73418-87-8)
- 3-(2,4-Dichlorophenoxy)propane-1-sulfonyl chloride (CAS 1018549-16-0)
- tert-Butyl 4-(4-bromophenoxy)piperidine-1-carboxylate (CAS 308386-38-1)
- Bromo-PEG3-C2-phosphonic acid (CAS 1148026-99-6)
- 7-(4-Chlorophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 241488-39-1)
- N-(2-Fluorobenzyl)-6-(1H-1,2,4-triazol-1-yl)pyridazine-3-carboxamide (CAS 1448033-45-1)
- 6'-Methoxy-2',3',4',9'-tetrahydrospiro[oxetane-3,1'-pyrido[3,4-b]indole] (CAS 1523558-67-9)
- 3-{[(3-methylphenyl)methyl]sulfanyl}-4H-1lambda6,4-benzothiazine-1,1-dione (CAS 477868-90-9)
- Furo[3,4-b]benzofuran (CAS 247-11-0)
- Methyl 2-bromo-5-(4-fluorophenyl)thiazole-4-carboxylate (CAS 1038508-94-9)
- Peptide 442 (CAS CATO-CPTD788442)
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