Flunarizine Impurity 10 CAS 345-92-6
| CAS No. | 345-92-6 |
| Molecular Formula | C13H8F2O |
| Molecular Weight | 218.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Flunarizine Impurity 10 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 218.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Flunarizine Impurity 10 (CAS 345-92-6) is a certified pharmaceutical impurity reference standard with the molecular formula C13H8F2O and a molecular weight of 218.20 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8F2O |
| Molecular Weight | 218.20 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Flunarizine Standards
- Flunarizine impurity 43 (CAS 1133842-25-7)
- Flunarizine Impurity 8 (CAS 365-24-2)
- Flunarizine Impurity 17 (CAS 17730-78-8)
- Flunarizine Impurity 18 (CAS 6416-39-3)
- Flunarizine Impurity 18 (CAS CATO-C4X-135718)
- Flunarizine impurity 42 (CAS CATO-C4X-135742)
- Flunarizine Impurity 31 (CAS CATO-C4X-135731)
- Flunarizine Impurity 59 (CAS 114312-65-1)
Recommended Standards
- Dimethyl (-)-2,3-O-Isopropylidene-L-tartrate (CAS 37031-29-1)
- Cabozantinib Impurity 27 (CAS 332-07-0)
- (+)-2,3-O-Isopropylidene-D-tartaric Acid Dimethyl Ester (4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylic Acid Dimethyl Ester 37031-30-4 Dimethyl (+)-2,3-O-Isopropylidene-D-tartrate Dimethyl (4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylate I0474 (CAS 37031-30-4)
- Remdesivir Impurity 16 (CAS CATO-C4X-210016)
- Pregabalin EP Impurity B/(R)-Pregabalin (CAS 148553-51-9)
- Coclaurine Impurity 15 (CAS CATO-C4X-27515)
- Epinastine Impurity N5 (CAS 21535-44-4)
- 3-Methyl-N-(4-phenylthiazol-2-yl)isoxazole-5-carboxamide (CAS 946229-32-9)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-methoxyphenyl)methanone (CAS 898757-55-6)
- 5,5'-(9H-Fluorene-2,7-diyl)diisophthalic acid (CAS 1424351-59-6)
- 60939-21-1 2-oxoacetamide DTXSID00470901 (CAS 60939-21-1)
- Alfadolone Acetate (CAS 23930-37-2)
- (3-amino-6-methylpyridin-2-yl)methanol (CAS 32398-86-0)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
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