Flunarizine Impurity 8 CAS 365-24-2

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.365-24-2
Molecular FormulaC13H10F2O
Molecular Weight220.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Flunarizine Impurity 8 CAS 365-24-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 220.21 g/mol gives Flunarizine Impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Flunarizine Impurity 8 (CAS 365-24-2), a pharmacopoeial impurity reference standard (molecular formula C13H10F2O, MW 220.21 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Flunarizine Impurity 8 (C13H10F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Flunarizine Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H10F2O
Molecular Weight220.21 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing

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