Ketotifen Hydrogen Fumarate CAS 34580-14-8
| CAS No. | 34580-14-8 |
| Molecular Formula | C19H19NOS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ketotifen Hydrogen Fumarate.
CATO supplies Ketotifen Hydrogen Fumarate (CAS 34580-14-8), a certified reference material (molecular formula C19H19NOSC4H4O4, MW 425.50 g/mol) for analytical method development and quality control.
The molecular framework of Ketotifen Hydrogen Fumarate (C19H19NOSC4H4O4) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H19NOS C4H4O4 |
| Molecular Weight | 425.50 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ketotifen Standards
- Ketotifen Impurity 23 (CAS 111428-56-9)
- Ketotifen Impurity 9 HCl (CAS 1227458-03-8)
- Ketotifen EP Impurity C (CAS 126939-27-3)
- Ketotifen EP Impurity E (CAS 1346603-71-1)
- Ketotifen EP Impurity F (Mixture of Enol and Ketone) (CAS 34580-09-1)
- Ketotifen (CAS 34580-13-7)
- Ketotifen Impurity 19 (CAS 34580-20-6)
- Ketotifen EP Impurity G (CAS 43076-16-0)
Recommended Standards
- 3-Methyl-4-{[(4-methylphenyl)amino]methylidene}-4,5-dihydro-1H-pyrazol-5-one (CAS 339020-92-7)
- 6-Oxo-1,6-dihydropyrimidine-5-sulfonyl chloride (CAS 1211581-63-3)
- (1Z)-1-{3-chloro-4-[(4-fluorophenyl)methoxy]phenyl}-N-(2,4-difluorophenyl)methanimine (CAS 297150-45-9)
- 3-((Tert-butoxycarbonyl)amino)hexanoic acid (CAS 282524-95-2)
- Ethyl 2-amino-4-(2,4-dimethylphenyl)thiophene-3-carboxylate (CAS 15854-10-1)
- (2Z)-2,3-Dichloro-3-{[(2-chlorophenyl)methyl]sulfanyl}-N-(6-methoxypyridin-3-yl)prop-2-enamide (CAS 337922-06-2)
- O,O-Dimethylphosphorothioic acid sodium (CAS 23754-87-2)
- Ethyl 4-bromofuran-2-carboxylate (CAS 58471-32-2)
- 4-(4-(Hydroxymethyl)piperidin-1-yl)benzaldehyde (CAS 683772-13-6)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com