4-[(4-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde CAS 345983-03-1
| CAS No. | 345983-03-1 |
| Molecular Formula | C16H14ClIO3 |
| Molecular Weight | 416.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-[(4-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde (C16H14ClIO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-[(4-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde (CAS 345983-03-1), molecular formula C16H14ClIO3 and molecular weight 416.64 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[(4-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14ClIO3 |
| Molecular Weight | 416.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/I-containing |
Related Chlorobenzyl Standards
- 4-[(2-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde (CAS 345985-65-1)
- 4-[(3-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde (CAS 384857-02-7)
- N-(4-chlorobenzyl)-N-(naphthalen-1-yl)-3-nitrobenzamide (CAS 337354-93-5)
- Methyl 2-[(4-chlorobenzyl)(phenylsulfonyl)amino]benzoate (CAS 1858257-24-5)
- 2-((n-(4-Chlorobenzyl)-4-methylphenyl)sulfonamido)benzoic acid (CAS 392313-52-9)
- Ethyl 2-{2-[({[(3-chlorobenzyl)oxy]imino}methyl)amino]-1,3-thiazol-4-yl}benzenecarboxylate (CAS 250713-84-9)
- 13-((4-Chlorobenzyl)oxy)-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-dione (CAS 478029-46-8)
- 2-((4-Chlorobenzyl)thio)-4,5-diphenyl-1-(prop-2-yn-1-yl)-1H-imidazole (CAS 339277-03-1)
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