4-[(2-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde CAS 345985-65-1
| CAS No. | 345985-65-1 |
| Molecular Formula | C16H14ClIO3 |
| Molecular Weight | 416.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(2-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde.
CATO supplies 4-[(2-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde (CAS 345985-65-1), a certified reference material (molecular formula C16H14ClIO3, MW 416.64 g/mol) for analytical method development and quality control.
The molecular framework of 4-[(2-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde (C16H14ClIO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H14ClIO3 |
| Molecular Weight | 416.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/I-containing |
Related Chlorobenzyl Standards
- 4-[(3-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde (CAS 384857-02-7)
- 4-[(4-Chlorobenzyl)oxy]-3-ethoxy-5-iodobenzaldehyde (CAS 345983-03-1)
- N-(4-chlorobenzyl)-N-(naphthalen-1-yl)-3-nitrobenzamide (CAS 337354-93-5)
- Methyl 2-[(4-chlorobenzyl)(phenylsulfonyl)amino]benzoate (CAS 1858257-24-5)
- 2-((n-(4-Chlorobenzyl)-4-methylphenyl)sulfonamido)benzoic acid (CAS 392313-52-9)
- Ethyl 2-{2-[({[(3-chlorobenzyl)oxy]imino}methyl)amino]-1,3-thiazol-4-yl}benzenecarboxylate (CAS 250713-84-9)
- 13-((4-Chlorobenzyl)oxy)-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-dione (CAS 478029-46-8)
- 2-((4-Chlorobenzyl)thio)-4,5-diphenyl-1-(prop-2-yn-1-yl)-1H-imidazole (CAS 339277-03-1)
Recommended Standards
- 3β-Hydroxy-5-cholestenoic Acid (CAS 6561-58-6)
- 3,27-Dihydroxy-5-cholesten-7-one (CAS 240129-30-0)
- 1α,25-Dihydroxy-7-dehydrocholesterol (CAS 61954-91-4)
- Cabraleahydroxylactone (CAS 35833-69-3)
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-hydroxy-7-methoxy-8-(pentyloxy)quinoline-3-carboxamide (CAS 282089-49-0)
- 5-Fluoro-1-(tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 68321-44-8)
- 2-(3,5-Dimethylphenyl)nicotinic acid (CAS 1226149-93-4)
- 2-(Benzyloxy)-4-bromo-5-methylbenzaldehyde (CAS 2056110-59-7)
- [2,2'-Binaphthalene]-1,1',4,4'-tetraone (CAS 3408-13-7)
- 1-(1,2,3,4-Tetrahydroquinolin-6-yl)cyclopropane-1-carboxylic acid (CAS 1895366-23-0)
- (Dimethylsulfamoyl)dimethylamine (CAS 3768-63-6)
- (R)-1-(Piperidin-3-yl)tetrahydropyrimidin-2(1H)-one hydrochloride (CAS 2680614-89-3)
- 2-((2-Methylthiazol-4-yl)methoxy)-4-propoxybenzaldehyde (CAS 923842-44-8)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
Why CATO?
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