Urapidil Impurity 3 CAS 34654-81-4
| CAS No. | 34654-81-4 |
| Molecular Formula | C9H14ClN3O2 |
| Molecular Weight | 231.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Urapidil Impurity 3 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 231.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Urapidil Impurity 3 (CAS 34654-81-4, C9H14ClN3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H14ClN3O2 |
| Molecular Weight | 231.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Urapidil Standards
- Urapidil Impurity 48 (CAS CATO-C4X-192448)
- Urapidil Impurity 93 (CAS 63987-50-8)
- Urapidil Impurity 45 (CAS CATO-C4X-192445)
- Urapidil Impurity 44 (CAS CATO-C4X-192444)
- Urapidil Impurity 87 (CAS CATO-C4X-192487)
- Urapidil Impurity 113 (CAS CATO-C4X-1924113)
- Urapidil Impurity 69 (CAS 117525-95-8)
- Urapidil Impurity 70 (CAS 112735-05-4)
Recommended Standards
- Alprazolam EP Impurity E (CAS 719-59-5)
- Temozolomide Impurity 25 (CAS 83-01-2)
- Trospium Impurity 19 (CAS 799283-74-2)
- Ezetimibe Impurity 50 (CAS 3369-35-5)
- Finasteride Impurity 49 (CAS CATO-C4X-164549)
- cis-Permethrin EP Impurity G (CAS 85576-82-5)
- Cefazolin Impurity 58 (CAS 1012-29-9)
- 5-Chloro-1-methyl-4-nitro-1H-pyrrole-2-carbaldehyde (CAS 1708380-42-0)
- 6-(Methylthio)-1-hexanol (CAS 98433-41-1)
- TAPI-0 (CAS 143457-40-3)
- N-Fmoc-D,L-γ-carboxyglutamic Acid γ,γ-Di-t-butyl Ester (CAS 308357-14-4)
- 1-Bromo-5-chloro-3-fluoro-2-(trifluoromethoxy)benzene (CAS 1417568-73-0)
- N,N-diethyl-6-mercaptopyridine-3-sulfonamide (CAS 852389-11-8)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com