Domperidone Impurity 39 CAS 34840-27-2

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.34840-27-2
Molecular FormulaC9H12N2O2
Molecular Weight180.20 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Domperidone Impurity 39 CAS 34840-27-2 chemical structure

Description

CATO supplies Domperidone Impurity 39 (CAS 34840-27-2), a pharmacopoeial impurity reference standard (molecular formula C9H12N2O2, MW 180.20 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C9H12N2O2, Domperidone Impurity 39 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 180.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H12N2O2
Molecular Weight180.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1966
Nitrogen Atoms2

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