3,5-Bis(trifluoromethyl)phenol CAS 349-58-6
| CAS No. | 349-58-6 |
| Molecular Formula | C8H4F6O |
| Molecular Weight | 230.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 230.11 g/mol gives 3,5-Bis(trifluoromethyl)phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3,5-Bis(trifluoromethyl)phenol (CAS 349-58-6) is a high-purity analytical reference standard with the molecular formula C8H4F6O and a molecular weight of 230.11 g/mol.
Based on its molecular formula C8H4F6O, 3,5-Bis(trifluoromethyl)phenol contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 230.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3,5-Bis(trifluoromethyl)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4F6O |
| Molecular Weight | 230.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
- 4,6-Bis(trifluoromethyl)pyridin-2-amine (CAS 112110-08-4)
- 3,5-Bis(trifluoromethyl)pyridin-2-amine (CAS 116593-01-2)
- 5,6-Bis(trifluoromethyl)pyridin-2-amine (CAS 1246466-56-7)
- 4,5-Bis-trifluoromethyl-pyridin-2-ylamine (CAS 176762-33-7)
- 2,5-Bis(trifluoromethyl)pyridin-3-amine (CAS 1803804-90-1)
- 2,4-Bis(trifluoromethyl)phenol (CAS 908848-70-4)
- 2,5-Bis(trifluoromethyl)phenol (CAS 779-88-4)
- 2,6-Bis(trifluoromethyl)phenol (CAS 46377-35-9)
Recommended Standards
- 3,4-BIs(trifluoromethyl)phenol (CAS 54850-27-0)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen piperazin-2-ylboronate (CAS 2223006-88-8)
- 3-(Difluoromethoxy)-4-fluorobenzotrifluoride (CAS 957146-67-7)
- 4-(2,4-Dichlorophenyl)-1,3-thiazole (CAS 383145-54-8)
- 2,3,6,7-Tetrabromoanthracene-9,10-dione (CAS 55805-84-0)
- 1-Bromo-3-(difluoromethoxy)-5-iodobenzene (CAS 1261775-70-5)
- 1-Benzyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 1132841-07-6)
- rac-[(2R,3R)-3-methyloxiran-2-yl]methanol (CAS 50468-21-8)
- [(3Z)-1-[(2,4-Dichlorophenyl)methyl]-5-nitro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino pentanoate (CAS 303998-06-3)
- 4-Cyclopropoxy-N,N-dimethyl-5-(trifluoromethyl)pyridin-2-amine (CAS 1243473-00-8)
- 2-(Thiophen-2-yl)benzo[d]oxazol-6-amine (CAS 52331-76-7)
- 4-bromo-2-chloro-6-methylaniline hydrochloride (CAS 1172914-08-7)
- 4-Chloro-5-(trifluoromethyl)-3,4-dihydroquinazoline (CAS 1823876-81-8)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com