1H-1,2,4-triazole-1-carboxamide CAS 35101-89-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1H-1,2,4-triazole-1-carboxamide.

1H-1,2,4-triazole-1-carboxamide (CAS 35101-89-4) is a high-purity analytical reference standard with the molecular formula C3H4N4O and a molecular weight of 112.09 g/mol.

Structurally, 1H-1,2,4-triazole-1-carboxamide (C3H4N4O) contains an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 112.09 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1H-1,2,4-triazole-1-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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