Pazopanib Impurity 31 CAS 35113-90-7
| CAS No. | 35113-90-7 |
| Molecular Formula | C8H9Cl2N |
| Molecular Weight | 190.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pazopanib Impurity 31.
CATO supplies Pazopanib Impurity 31 (CAS 35113-90-7), a certified reference material (molecular formula C8H9Cl2N, MW 190.07 g/mol) for analytical method development and quality control.
The molecular framework of Pazopanib Impurity 31 (C8H9Cl2N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9Cl2N |
| Molecular Weight | 190.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pazopanib Standards
- Pazopanib Impurity 10 (CAS CATO-C4X-172510)
- Pazopanib Impurity 2 (CAS 1354224-47-7)
- Pazopanib Impurity 22 (CAS 444731-73-1)
- Pazopanib Impurity 45(Mixture of Isomers) (CAS CATO-C4X-172545)
- Pazopanib Impurity 19 (CAS 6973-09-7)
- Pazopanib Impurity 25 (CAS 6274-28-8)
- Pazopanib Impurity 35 (CAS CATO-C4X-172535)
- Pazopanib Impurity 30 (CAS 1313372-75-6)
Recommended Standards
- N-Methyl-3,4-dichlorobenzylamine (CAS 5635-67-6)
- Esomeprazole Impurity 100 (CAS 142885-96-9)
- N-Methyl-2,4-dichlorobenzylamine (CAS 5013-77-4)
- Omeprazole Impurity 24 (CAS 109371-17-7)
- 2-(2,6-Difluoro-4-(trifluoromethyl)phenoxy)-4-fluoroaniline (CAS 2244088-77-3)
- Diethyl (3,3-diphenylallyl)phosphonate (CAS 91861-56-2)
- 4-[(1E)-[(3-Chloro-4-fluorophenyl)imino]methyl]phenyl 4-methylbenzoate (CAS 331460-60-7)
- N1-Dansyl spermine, 96% (CAS 191410-24-9)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)propan-1-amine (CAS 1270540-71-0)
- [(1-Methyl-1h-pyrrol-2-yl)methyl](prop-2-en-1-yl)amine (CAS 880809-20-1)
- ethyl 7-amino-5-methyl-3-phenyl-1H-indole-2-carboxylate (CAS 1171609-85-0)
- ethyl 3-amino-5-bromothieno[2,3-b]pyridine-2-carboxylate (CAS 1234616-31-9)
- 2-(Adamantan-2-yl)ethan-1-amine (CAS 59807-53-3)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com