Nicergoline EP Impurity C CAS 35155-28-3
| CAS No. | 35155-28-3 |
| Molecular Formula | C18H24N2O2 |
| Molecular Weight | 300.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nicergoline EP Impurity C (CAS 35155-28-3), a pharmacopoeial impurity reference standard (molecular formula C18H24N2O2, MW 300.40 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Nicergoline EP Impurity C (C18H24N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H24N2O2 |
| Molecular Weight | 300.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 2 |
Related Nicergoline Standards
- Nicergoline Impurity 11 (CAS CATO-C4X-208511)
- Nicergoline Impurity 18 (CAS CATO-C4X-208518)
- Nicergoline Impurity 14 (CAS CATO-C4X-208514)
- Nicergoline Impurity 9 (CAS 23495-65-0)
- Nicergoline Impurity 21 (CAS 23495-64-9)
- Nicergoline Impurity 20 (CAS CATO-C4X-208520)
- Nicergoline Impurity 12 (CAS 35121-60-9)
- Nicergoline Impurity 22 (CAS CATO-C4X-208522)
Recommended Standards
- Peramivir Impurity 44 (CAS CATO-C4X-183344)
- Epalrestat Impurity 56 (CAS CATO-C4X-223656)
- Mianserin impurity 40 (CAS CATO-C4X-136940)
- Bixalomer Impurity 1 (CAS 120239-62-5)
- Atrasentan Impurity 146 (CAS 1058350-25-6)
- Semaglutide impurity 193 (CAS CATO-C4X-2226193)
- Polymyxin Impurity 56 X Trifluoroacetate (CAS 3034660-94-8 (free base))
- (3-Bromo-5,7-dimethyladamantan-1-yl)methanol (CAS 1430846-38-0)
- 3-(Cyclohexyloxy)-5-methylphenol (CAS 1243405-09-5)
- 5-(4-(Benzyloxy)-3-bromophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706449-31-1)
- 6-Chloro-2-(methoxymethyl)-N-methylpyrimidin-4-amine (CAS 1490224-67-3)
- Ethyl 2-3-4-6-tetra-O-acetyl-α-D-thioglucopyranoside (CAS 41670-79-5)
- (S)-2-Amino-3-(4-guanidinophenyl)propanoic acid (CAS 59574-11-7)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com