1-[4-chloro-3-(trifluoromethyl)phenyl]propan-2-one CAS 35172-95-3

Purity 97%+In StockPharmaceutical Standards
CAS No.35172-95-3
Molecular FormulaC10H8ClF3O
Molecular Weight236.62 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-[4-chloro-3-(trifluoromethyl)phenyl]propan-2-one CAS 35172-95-3 chemical structure

Description

The occurrence of 1-[4-chloro-3-(trifluoromethyl)phenyl]propan-2-one is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1-[4-chloro-3-(trifluoromethyl)phenyl]propan-2-one (CAS 35172-95-3), a certified reference material (molecular formula C10H8ClF3O, MW 236.62 g/mol) for analytical method development and quality control.

Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 1-[4-chloro-3-(trifluoromethyl)phenyl]propan-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-[4-chloro-3-(trifluoromethyl)phenyl]propan-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H8ClF3O
Molecular Weight236.62 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967
Halogen ContentF/Cl-containing

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