4-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde CAS 35295-36-4
| CAS No. | 35295-36-4 |
| Molecular Formula | C9H6F4O2 |
| Molecular Weight | 222.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde (CAS 35295-36-4) is a high-purity analytical reference standard with the molecular formula C9H6F4O2 and a molecular weight of 222.14 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6F4O2 |
| Molecular Weight | 222.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F-containing |
Related Tetrafluoroethoxy Standards
- 2-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde (CAS 85187-22-0)
- 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde (CAS 35295-35-3)
- (4-(1,1,2,2-Tetrafluoroethoxy)phenyl)methanol (CAS 773868-39-6)
- 4-(1,1,2,2-Tetrafluoroethoxy)benzene-1,3-diamine (CAS 61988-37-2)
- 2-(1,1,2,2-tetrafluoroethoxy)phenol (CAS 88553-88-2)
- 3-(1,1,2,2-Tetrafluoroethoxy)phenol (CAS 53997-99-2)
- 4-(1,1,2,2-Tetrafluoroethoxy)phenol (CAS 85578-29-6)
- 2-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS 35295-34-2)
Recommended Standards
- 3-Fluoro-4-(trifluoromethyl)phenylacetic Acid (CAS 238754-67-1)
- 4-Fluoro-2-(trifluoromethyl)benzhydrazide (CAS 887267-54-1)
- 3-Fluoro-4-(2,2,2-trifluoroethoxy)benzaldehyde (CAS 502486-73-9)
- 4-Fluoro-2-methyl-3-(trifluoromethyl)benzoic acid (CAS 2167320-60-5)
- Ethyl 4-carbamoylbicyclo[2.2.2]octane-1-carboxylate (CAS 79663-72-2)
- cis-1-Amino-3-[(benzyloxy)methyl]cyclobutane-1-carboxylic acid (CAS 1358884-51-1)
- 1-Cyclopropylpiperidine-3-carboxylic acid (CAS 939757-41-2)
- N-isopropyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide hydrochloride (CAS 1220036-91-8)
- N-Allyl-5-amino-4-fluoro-2-methylbenzamide (CAS 1875031-34-7)
- (2S,3R,4R,5S,6R)-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol (CAS 1336-90-9)
- 1-Amino-2-methyl-3-(morpholin-4-yl)propan-2-ol (CAS 1339167-59-7)
- Celecoxib Impurity 60 (CAS CATO-C4X-104360)
- (E)-{[1-(4-methoxyphenyl)-4-[(4-methylphenyl)sulfanyl]-2-phenyl-6,7-dihydro-1H-indol-5-yl]methylidene}(propan-2-yl)amine (CAS 477869-24-2)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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