2-Methyl-1H-imidazo[4,5-h]quinolin-5-amine CAS 35313-63-4

Purity 97%+In StockPharmaceutical Standards
CAS No.35313-63-4
Molecular FormulaC11H10N4
Molecular Weight198.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Methyl-1H-imidazo[4,5-h]quinolin-5-amine CAS 35313-63-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Methyl-1H-imidazo[4,5-h]quinolin-5-amine.

2-Methyl-1H-imidazo[4,5-h]quinolin-5-amine (CAS 35313-63-4) is a high-purity analytical reference standard with the molecular formula C11H10N4 and a molecular weight of 198.22 g/mol.

The molecular framework of 2-Methyl-1H-imidazo[4,5-h]quinolin-5-amine (C11H10N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H10N4
Molecular Weight198.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967
Nitrogen Atoms4

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