Ethyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-pyran-3-carboxylate CAS 354556-46-0
| CAS No. | 354556-46-0 |
| Molecular Formula | C27H25FN4O3S |
| Molecular Weight | 504.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-pyran-3-carboxylate (CAS 354556-46-0), molecular formula C27H25FN4O3S and molecular weight 504.58 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-pyran-3-carboxylate (C27H25FN4O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-pyran-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H25FN4O3S |
| Molecular Weight | 504.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- Methyl 6-amino-5-cyano-2-(((3-cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-pyran-3-carboxylate (CAS 354556-45-9)
- 2-Amino-4-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-1-(1,3-dihydro-2H-isoindol-2-yl)-1,4-butaned (CAS 847928-32-9)
- 3-Amino-6-methyl-4-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (CAS 445382-88-7)
- 3-Amino-N-(2,4-dimethylphenyl)-4-methylbenzamide (CAS 6370-19-0)
- 3-Amino-4-(2-chlorophenyl)-N-(4-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332372-56-2)
- 3-Amino-N-(2,3-dichlorophenyl)-4-phenyl-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444153-42-8)
- 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one (CAS 1193165-26-2)
- 3-Amino-6-(3,4-dimethoxybenzyl)-N-(4-fluorophenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 939889-21-1)
Recommended Standards
- 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(6-isocyanatohexyl)- (CAS 3779-63-3)
- (4S,4′S)-2,2′-(5,5′-Dimethoxy[1,1′-biphenyl]-2,2′-diyl)bis[4,5-dihydro-4-phenyloxazole] (CAS 944133-17-9)
- Ticagrelor Impurity 14 (CAS 1643378-47-5)
- 4,4'-(5'-(4-(1H-Pyrazol-4-yl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)bis(1H-pyrazole) (CAS 1855846-73-9)
- 2-Methyladamantan-2-yl acrylate (CAS 249562-06-9)
- 3-Bromo-2-chloro-5-fluoroaniline hydrochloride (CAS 1269233-61-5)
- 2-((3-Cyano-4-(3,4-dimethoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(3-nitrophenyl)acetamide (CAS 332018-57-2)
- 2-((4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 578001-34-0)
- N-Ethyl-1-(piperidin-4-yl)pyrrolidine-2-carboxamide (CAS 1251222-03-3)
- (1,4,5,7-Tetrahydropyrano[3,4-c]pyrazol-4-yl)methanol (CAS 1422344-45-3)
- (2R,3S,4R,5R)-2-(allyloxy)tetrahydro-2H-pyran-3,4,5-triol (CAS 130450-63-4)
- Tofacitinib Impurity 239 (CAS CATO-C4X-1079239)
- 4-(1-chloroethyl)-1,2-difluorobenzene (CAS 221031-54-5)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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