3-Methoxy-6-nitro-1H-indole CAS 354807-14-0
| CAS No. | 354807-14-0 |
| Molecular Formula | C9H8N2O3 |
| Molecular Weight | 192.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.17 g/mol gives 3-Methoxy-6-nitro-1H-indole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Methoxy-6-nitro-1H-indole (CAS 354807-14-0), a certified reference material (molecular formula C9H8N2O3, MW 192.17 g/mol) for analytical method development and quality control.
3-Methoxy-6-nitro-1H-indole (C9H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Methoxy-6-nitro-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O3 |
| Molecular Weight | 192.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 4-Methoxy-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid (CAS 1000341-34-3)
- 2-(3-Methoxy-4-nitrophenyl)acetonitrile (CAS 104103-16-4)
- 2-(4-Methoxy-2-nitrophenyl)acetonitrile (CAS 105003-90-5)
- 5-Methoxy-7-nitro-1H-indole (CAS 10553-10-3)
- 5-Methoxy-2-methyl-3-nitrobenzonitrile (CAS 1082040-58-1)
- 6-Methoxy-1H-indazole-5-carboxylic Acid (CAS 1082041-60-8)
- 2-(3-methoxy-2-nitrophenyl)acetonitrile (CAS 111795-89-2)
- 4-Methoxy-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1190311-20-6)
Recommended Standards
- 3-Methoxy-2-methyl-6-nitrobenzonitrile (CAS 213987-66-7)
- 3-Methoxyquinazoline-2,4(1H,3H)-dione (CAS 41120-18-7)
- 3-Ethyl-5-nitrobenzo[d]isoxazole (CAS 66048-16-6)
- 3-Methyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazole-5-carboxylic acid (CAS 863564-77-6)
- Methyl 3-(4-chlorophenyl)-2-methylbenzoate (CAS 1820607-07-5)
- 4-Chloro-2-methyl-5-(((1-methyl-1H-pyrazol-3-yl)methyl)amino)pyridazin-3(2H)-one (CAS 1776030-18-2)
- 1-(2-Cyclopropyl-5,6,7,8-tetrahydroquinazolin-4-yl)-1H-pyrazole-3-carboxylic acid (CAS 1710846-02-8)
- 4-(4-Nitrophenoxy)-1,5-diphenyl-3-(trifluoromethyl)-1H-pyrazole (CAS 400086-89-7)
- (S)-1-(2-Chloro-6-fluorophenyl)ethanamine hydrochloride (CAS 1000878-48-7)
- 1-(4-Fluorobenzyl)-1h-indole-2,3-dione (CAS 313245-18-0)
- 4-Bromo-3,6-dichloro-2-fluorobenzaldehyde (CAS 1160573-29-4)
- Indobufen Impurity 53 (CAS CATO-C4X-179253)
- 5-((3,4-Dimethoxy-5-(methylselanyl)phenyl)(hydroxy)methyl)-2-methoxyphenol (CAS 2123477-91-6)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
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