3-Ethyl-5-nitrobenzo[d]isoxazole CAS 66048-16-6
| CAS No. | 66048-16-6 |
| Molecular Formula | C9H8N2O3 |
| Molecular Weight | 192.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Ethyl-5-nitrobenzo[d]isoxazole (CAS 66048-16-6) is a high-purity analytical reference standard with the molecular formula C9H8N2O3 and a molecular weight of 192.17 g/mol.
Based on its molecular formula C9H8N2O3, 3-Ethyl-5-nitrobenzo[d]isoxazole contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 192.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Ethyl-5-nitrobenzo[d]isoxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O3 |
| Molecular Weight | 192.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 4-Ethyl-2-nitrobenzo[d]oxazole (CAS 1806325-92-7)
- 7-Nitrobenzo[d][1,2,3]triazin-4(3H)-one (CAS 176260-31-4)
- 6-Nitrobenzo[d][1,2,3]triazin-4(3h)-one (CAS 91532-29-5)
- 6-Nitrobenzo[d][1,3]dioxole-5-carbonitrile (CAS 52805-38-6)
- 6-Nitrobenzo[d]oxazole-2-carbaldehyde (CAS 944907-40-8)
- 3-Methyl-5-nitrobenzo[d]oxazol-2(3H)-one (CAS 101084-60-0)
- 3-Methyl-6-nitrobenzo[d]oxazol-2(3H)-one (CAS 101084-61-1)
- (6-Nitrobenzo[d]isoxazol-3-yl)methanol (CAS 102741-52-6)
Recommended Standards
- 3,4-Dihydro-6-nitro-2(1H)-quinolinone (CAS 22246-16-8)
- 3-Methoxy-2-methyl-6-nitrobenzonitrile (CAS 213987-66-7)
- 3-(Pyridin-3-yl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 264606-31-7)
- 3-Methoxy-6-nitro-1H-indole (CAS 354807-14-0)
- 5-(1-Amino-2-(1H-1,2,4-triazol-1-yl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 338405-47-3)
- 2H-Pyran-4-amine, N-(5-bromo-2-nitrophenyl)tetrahydro- (CAS 1162696-22-1)
- 1,1-Dimethyl-1,2,3,4-tetrahydronaphthalene (CAS 1985-59-7)
- 4-((2-Chloro-6-fluorobenzyl)oxy)-3-methoxybenzoic acid (CAS 773872-82-5)
- Methyl 2-iodo-8-methoxyindolizine-7-carboxylate (CAS 1706444-99-6)
- 1-(3-Aminoazetidin-1-yl)-2-methylpropan-2-ol dimethanesulfonate (CAS 2044927-35-5)
- 1-[[2-(Dimethoxymethyl)-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl]methyl]-4-methylpiperazin-2-one (CAS 1708975-38-5)
- Aclidinium bromide Impurity 12 (CAS 320347-97-5)
- 3-Amino-4-methoxy-2-(trifluoromethyl)pyridine (CAS 1227581-96-5)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
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