Trazodone impurity 50 CAS 355396-54-2
| CAS No. | 355396-54-2 |
| Molecular Formula | C18H20Cl2N2 |
| Molecular Weight | 335.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Trazodone impurity 50 (C18H20Cl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 335.27 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Trazodone impurity 50 (CAS 355396-54-2), a pharmacopoeial impurity reference standard (molecular formula C18H20Cl2N2, MW 335.27 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Trazodone impurity 50 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20Cl2N2 |
| Molecular Weight | 335.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trazodone Standards
- Trazodone EP Impurity B (CAS 62337-66-0)
- Trazodone Impurity 34 (CAS CATO-C4X-177234)
- Trazodone impurity 52 (CAS CATO-C4X-177252)
- Trazodone Impurity 107 (CAS CATO-C4X-1772107)
- Trazodone impurity 40 (CAS 328410-01-1)
- Trazodone EP Impurity G (CAS 2470436-00-9)
- Trazodone Impurity 3 (CAS CATO-C4X-17723)
- Trazodone Impurity 30 (CAS 79975-63-6)
Recommended Standards
- Methyl 4-bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-5-carboxylate (CAS 2387597-15-9)
- Suzetrigine Impurity 4 (CAS 2875067-17-5)
- Methyl 2-bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-4-carboxylate (CAS 885704-79-0)
- ethyl 3-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate (CAS 1018125-43-3)
- Bisoprolol EP Impurity Q Hemifumarate (CAS CATO-C4X-124744)
- Cabozantinib Impurity 18 (CAS CATO-C4X-201818)
- Morinidazole Impurity 21 (CAS CATO-C4X-219621)
- 2-Amino-1-((S)-2-((benzyl(ethyl)amino)methyl)pyrrolidin-1-yl)-3-methylbutan-1-one (CAS 1354026-65-5)
- 2-(2,4-Dioxo-1,2-dihydropyrido[3,2-d]pyrimidin-3(4H)-yl)propanoic acid (CAS 552298-13-2)
- 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-(3-(trifluoromethyl)benzyl)pyridin-2(1H)-one (CAS 477860-63-2)
- 3-Bromo-2-(difluoromethoxy)benzaldehyde (CAS 1249999-12-9)
- trans-(3-Methoxycyclobutyl)hydrazine (CAS 2166932-81-4)
- N,N-Dimethyl-4-nitrobenzamide (CAS 7291-01-2)
- Osteogenic Growth Peptide (10-14) (CAS 105250-85-9)
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