Favipiravir Impurity 8 CAS 356783-29-4
| CAS No. | 356783-29-4 |
| Molecular Formula | C5H3F2N3O |
| Molecular Weight | 159.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Favipiravir Impurity 8 (C5H3F2N3O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Favipiravir Impurity 8 (CAS 356783-29-4, C5H3F2N3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Favipiravir Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3F2N3O |
| Molecular Weight | 159.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Favipiravir Standards
- Favipiravir-13C3 (CAS CATO-C4X-210210)
- Favipiravir-13C3 (CAS CATO-CCAD303706)
- Favipiravir Impurity 9 (CAS 1079990-21-8)
- Favipiravir Impurity 20 (CAS 356783-49-8)
- Favipiravir Impurity 37 (CAS 259794-01-9)
- Favipiravir (CAS 259793-96-9)
- Favipiravir Impurity 21 (CAS 1207609-52-6)
- Favipiravir Impurity 6 (CAS 1374986-27-2)
Recommended Standards
- 1,4-difluoro-2-nitrobenzene (CAS 364-74-9)
- (S)-4-Hydroxy-2,5-dioxoimidazolidine-4-carboxamide (CAS 151359-23-8)
- 2,6-difluoronitrobenzene (CAS 19064-24-5)
- (R)-4-Hydroxy-2,5-dioxoimidazolidine-4-carboxamide (CAS 151359-26-1)
- Brivaracetam Impurity 179 (CAS CATO-C4X-2007179)
- Dexrazoxane Impurity 17 (CAS CATO-C4X-202017)
- Cidofovir Impurity 1 (CAS 133868-60-7)
- 8-Chloro-2-(2-thienyl)quinoline-4-carbonyl chloride (CAS 1160256-77-8)
- 3-[(Boc-amino)methyl]pyrrolidin-3-ol (CAS 125033-59-2)
- rac-Hesperetin (CAS 69097-99-0)
- (R)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-amine (CAS 221179-34-6)
- Celecoxib Impurity 77 (CAS CATO-C4X-104377)
- 5-bromo-1,3-dimethyl-2,3-dihydro-1H-1,3-benzodiazol-2-one (CAS 53439-89-7)
- D-Trp25-Tirzepatide (CAS CATO-CPTD788909)
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