1,4-difluoro-2-nitrobenzene CAS 364-74-9
| CAS No. | 364-74-9 |
| Molecular Formula | C6H3F2NO2 |
| Molecular Weight | 159.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 159.09 g/mol gives 1,4-difluoro-2-nitrobenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1,4-difluoro-2-nitrobenzene (CAS 364-74-9), molecular formula C6H3F2NO2 and molecular weight 159.09 g/mol, is a CATO reference standard with documented purity and traceability.
1,4-difluoro-2-nitrobenzene (C6H3F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1,4-difluoro-2-nitrobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3F2NO2 |
| Molecular Weight | 159.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related difluoro Standards
- 2,6-Difluoro-4-pyridinecarboxylic Acid (CAS 88912-23-6)
- 3,6-Difluoro pyridine-2-carboxylic acid 3,6-Difluoro-2-pyridinecarboxylic acid;3,6-difluoropicolinic acid 851386-45-3 A26073 (CAS 851386-45-3)
- 2,4-Difluoro-1-nitrobenzene (CAS 446-35-5)
- 4,5-Difluoro-2-methoxyaniline (CAS 1017779-71-3)
- 3,4-Difluoro-2-methoxyaniline (CAS 114076-35-6)
- 3,4-Difluoro-5-methoxyaniline (CAS 1195190-12-5)
- 3,6-Difluoro-2-methoxyaniline (CAS 1261677-79-5)
- 1378595-64-2 2,2-difluoro-1-(pyridin-4-yl)ethan-1-ol (CAS 1378595-64-2)
Recommended Standards
- 2,6-difluoronitrobenzene (CAS 19064-24-5)
- Favipiravir Impurity 8 (CAS 356783-29-4)
- (S)-4-Hydroxy-2,5-dioxoimidazolidine-4-carboxamide (CAS 151359-23-8)
- Linezolid Impurity 13 (CAS 369-34-6)
- cis-2,5-Dimethyl-morpholine (CAS 68043-56-1)
- 3-Amino-N-(2-ethoxyphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496019-13-7)
- Sodium 5-bromo-3-methylpicolinate (CAS 1956323-99-1)
- 3-(Trifluoromethyl)benzene-1,2,4,5-tetracarboxylic acid (CAS 53812-59-2)
- 4-((Benzyloxy)methyl)-1-(cyclopropylmethyl)-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine (CAS 1422138-49-5)
- 8-Bromo-7-methylquinoline (CAS 98203-08-8)
- Diethyl 1H-1,2,3-triazole-4,5-dicarboxylate (CAS 55357-63-6)
- N-(Pyrrolidin-2-ylmethyl)naphthalen-1-amine dioxalate (CAS 1177290-60-6)
- 1,1'-Sulfonyldiimidazole 1,1'-sulfonylbis(1H-imidazole) 7189-69-7 (CAS 7189-69-7)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com