(6-Chlorochroman-3-yl)methanol CAS 357396-09-9
| CAS No. | 357396-09-9 |
| Molecular Formula | C10H11ClO2 |
| Molecular Weight | 198.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (6-Chlorochroman-3-yl)methanol (C10H11ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(6-Chlorochroman-3-yl)methanol (CAS 357396-09-9) is a high-purity analytical reference standard with the molecular formula C10H11ClO2 and a molecular weight of 198.65 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (6-Chlorochroman-3-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO2 |
| Molecular Weight | 198.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Chlorochroman Standards
- (6-Chlorochroman-2-yl)methanamine (CAS 1271737-32-6)
- (6-Chlorochroman-3-yl)methanamine (CAS 885271-38-5)
- 5-Chlorochroman-3-carboxylic acid (CAS 1269695-63-7)
- 6-Chlorochroman-2-carboxylic acid (CAS 40026-24-2)
- 6-Chlorochroman-4-carboxylic Acid (CAS 76301-94-5)
- 8-Chlorochroman-3-carboxylic acid (CAS 885270-82-6)
- 8-Chlorochroman-7-ol (CAS 1256255-23-8)
- (R)-6-chlorochroman-4-ol (CAS 1270284-06-4)
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