Ibuprofen impurity 142 CAS 3585-52-2（free base)

Description

Compared with other compounds in its class, the molecular weight of 200.21 g/mol gives Ibuprofen impurity 142 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ibuprofen impurity 142 (CAS 3585-52-2（free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C11H13O2Na and a molecular weight of 200.21 g/mol.

The molecular framework of Ibuprofen impurity 142 (C11H13O2Na) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Ibuprofen impurity 142 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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