Calcium Dobesilate Impurity N2 CAS 35857-70-6
| CAS No. | 35857-70-6 |
| Molecular Formula | C6H6O5S |
| Molecular Weight | 190.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Calcium Dobesilate Impurity N2 (CAS 35857-70-6, C6H6O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carbohydrate-derived structure, a sulfone group, Calcium Dobesilate Impurity N2 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Calcium Dobesilate Impurity N2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6O5S |
| Molecular Weight | 190.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Sulfur Atoms | 1 |
Related Calcium Standards
- Calcium Dobesilate Impurity N5 (CAS 7134-09-0)
- Calcium Dobesilate Impurity N1 (CAS 6409-58-1)
- Calcium Dobesilate Impurity 19 (CAS 17724-07-1)
- Calcium Dobesilate Impurity 3 (CAS CATO-C4X-20513)
- Calcium Dobesilate Impurity 2 (CAS CATO-C4X-20512)
- Calcium Dobesilate Impurity 23 (CAS CATO-C4X-205123)
- Calcium Dobesilate Impurity 4 (CAS 2429952-20-3)
- Calcium Dobesilate Impurity 26 (CAS CATO-C4X-205126)
Recommended Standards
- Bis(2-Fluoroethyl) Sulfate (CAS 381-46-4)
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- N1-Methyl-4-(trifluoromethyl)benzene-1,2-diamine (CAS 35203-49-7)
- Ertugliflozin impurity 38 (CAS CATO-C4X-301138)
- (1R,3r,5S)-Ipratropium Impurity 40 (CAS 99888-00-3)
- Lasmiditan Impurity 1 (CAS 79538-29-7)
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- N-Cyclopentyl-4-methoxybenzamide (CAS 346720-43-2)
- 18-Oxooctadecanoic acid (CAS 176108-52-4)
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- 5-(Thiophen-2-yl)-1H-1,2,3-triazole (CAS 369363-68-8)
- Alanylserine (CAS 3062-19-9)
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