N-(4-Ethoxyphenyl)thiophene-2-sulfonamide CAS 358666-72-5

Purity 97%+In StockPharmaceutical Standards
CAS No.358666-72-5
Molecular FormulaC12H13NO3S2
Molecular Weight283.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Ethoxyphenyl)thiophene-2-sulfonamide CAS 358666-72-5 chemical structure

Description

The occurrence of N-(4-Ethoxyphenyl)thiophene-2-sulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(4-Ethoxyphenyl)thiophene-2-sulfonamide (CAS 358666-72-5), molecular formula C12H13NO3S2 and molecular weight 283.37 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-(4-Ethoxyphenyl)thiophene-2-sulfonamide (C12H13NO3S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-(4-Ethoxyphenyl)thiophene-2-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H13NO3S2
Molecular Weight283.37 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1
Sulfur Atoms2

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