Entecavir Impurity 45 CAS 3587-60-8

Description

Compared with other compounds in its class, the molecular weight of 156.61 g/mol gives Entecavir Impurity 45 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Entecavir Impurity 45 (CAS 3587-60-8), a pharmacopoeial impurity reference standard (molecular formula C8H9ClO, MW 156.61 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Entecavir Impurity 45 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 156.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Entecavir Impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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