Ibuprofen EP Impurity P CAS 36039-36-8

Description

The occurrence of Ibuprofen EP Impurity P is closely related to a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Ibuprofen EP Impurity P (CAS 36039-36-8), a pharmacopoeial impurity reference standard (molecular formula C13H20O, MW 192.30 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Ibuprofen EP Impurity P (C13H20O) is characterized by a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Ibuprofen EP Impurity P meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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