4-Acetamido-2-fluorobenzoic acid CAS 364-84-1
| CAS No. | 364-84-1 |
| Molecular Formula | C9H8FNO3 |
| Molecular Weight | 197.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Acetamido-2-fluorobenzoic acid (CAS 364-84-1) is a high-purity analytical reference standard with the molecular formula C9H8FNO3 and a molecular weight of 197.16 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-Acetamido-2-fluorobenzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 197.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Acetamido-2-fluorobenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8FNO3 |
| Molecular Weight | 197.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Acetamido Standards
- 2-Acetamido-3-fluorobenzoic acid (CAS 550346-18-4)
- 2-Acetamido-4-fluorobenzoic acid (CAS 394-27-4)
- 2-Acetamido-5-fluorobenzoic Acid (CAS 49579-56-8)
- 2-acetamido-6-fluorobenzoic acid (CAS 70413-91-1)
- 3-acetamido-4-fluorobenzoic acid (CAS 401-37-6)
- 4-Acetamido-3-fluorobenzoic acid (CAS 713-11-1)
- 5-Acetamido-2-fluorobenzoic acid (CAS 939909-22-5)
- 2-Acetamido-4-nitropyridine 1-oxide (CAS 4487-48-3)
Recommended Standards
- 4-(Trifluoromethyl)quinoline (CAS 25199-77-3)
- 4-(Furan-2-ylmethoxy)-4-oxobutanoic acid (CAS 412946-38-4)
- 5-(Trifluoromethyl)quinoline (CAS 342-30-3)
- 4-(3,3,3-Trifluoroprop-1-en-2-yl)benzonitrile (CAS 471856-97-0)
- Fenoldopam Impurity 1 (CAS 71636-38-9)
- (2-methylbutyl)({[1,2,4]triazolo[4,3-a]pyridin-3-yl}methyl)amine (CAS 1042565-20-7)
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- 1H,2H,3H,4H-pyrazino[1,2-a]indole hydrochloride (CAS 18637-52-0)
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- 2-(2,3-Dichlorophenoxy)-3,3,3-trifluoropropan-1-amine (CAS 886764-19-8)
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