N-Dechloroethyl Cyclophosphamide CAS 36761-83-8

Purity 97%+In StockPharmaceutical Standards
CAS No.36761-83-8
Molecular FormulaC5H12ClN2O2P
Molecular Weight198.59 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-Dechloroethyl Cyclophosphamide CAS 36761-83-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-Dechloroethyl Cyclophosphamide.

N-Dechloroethyl Cyclophosphamide (CAS 36761-83-8) is a high-purity analytical reference standard with the molecular formula C5H12ClN2O2P and a molecular weight of 198.59 g/mol.

The molecular framework of N-Dechloroethyl Cyclophosphamide (C5H12ClN2O2P) is characterized by an amide group, organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), N-Dechloroethyl Cyclophosphamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H12ClN2O2P
Molecular Weight198.59 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)0.5
CAS Registry Year (est.)1967
Halogen ContentCl-containing
Nitrogen Atoms2

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