Metformin EP Impurity E Sulfate CAS 36801-25-9
| CAS No. | 36801-25-9 |
| Molecular Formula | C3H9N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Metformin EP Impurity E Sulfate (CAS 36801-25-9, C3H9N5H2O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C3H9N5H2O4S, Metformin EP Impurity E Sulfate contains an amide group, a sulfone group, a carboxylic acid group, an ether linkage; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 213.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Metformin EP Impurity E Sulfate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H9N5 H2O4S |
| Molecular Weight | 213.21 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Metformin Standards
- Metformin EP Impurity D (CAS 108-78-1)
- Metformin Hydrochloride (CAS 1115-70-4)
- Metformin-d6 Hydrochloride (CAS 1185166-01-1)
- Metformin Impurity 38 (CAS 118632-64-7)
- Metformin EP impurity F Tetrahydrofuran Solution (CAS 124-40-3 (free base))
- Metformin Impurity 532 (CAS 141-83-3)
- Metformin Impurity N74 (CAS 1609-00-3)
- Metformin EP Impurity E HCl (CAS 1674-62-0)
Recommended Standards
- Relugolix Impurity 207 (CAS CATO-C4X-2429207)
- Cholesterol Impurity 6 (CAS 1251-98-5)
- Piperazine Impurity 27 (CAS 7040-23-5)
- 3-(2-Phenyl-1H-indol-1-yl)propanenitrile (CAS 19931-87-4)
- 4-((3H-purin-6-yl)amino)butanoic acid (CAS 31918-48-6)
- 2,4-Dichloro-6-(difluoromethoxy)anisole (CAS 1807184-14-0)
- 1-(3,4-Difluorobenzyl)-1H-pyrrole-2-carbaldehyde (CAS 1250679-87-8)
- 2-Methyl-N-(pyrrolidin-3-yl)pyrimidin-4-amine (CAS 1339212-98-4)
- 4-Chloro-3-iodo-1-methyl-1H-indazole (CAS 101584-65-0)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com