Cefamandole EP Impurity C CAS 36922-15-3
| CAS No. | 36922-15-3 |
| Molecular Formula | C20H20N6O6S2 |
| Molecular Weight | 504.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C20H20N6O6S2, Cefamandole EP Impurity C contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 504.54 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Cefamandole EP Impurity C (CAS 36922-15-3, C20H20N6O6S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H20N6O6S2 |
| Molecular Weight | 504.54 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Cefamandole Standards
- Cefamandole Oxide Impurity 15 (CAS CATO-C4X-122115)
- Cefamandole Impurity 17 (CAS CATO-C4X-122117)
- Cefamandole Impurity 9 (CAS CATO-C4X-12219)
- Cefamandole Impurity 12 (CAS CATO-C4X-122112)
- Cefamandole Impurity 23 (CAS CATO-C4X-122123)
- Cefamandole Impurity 24 (CAS CATO-C4X-122124)
- Cefamandole Impurity 6 (CAS CATO-C4X-12216)
- Cefamandole Impurity 11 (CAS CATO-C4X-122111)
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