Tadalafil Impurity 77 CAS 2064212-00-4
| CAS No. | 2064212-00-4 |
| Molecular Formula | C30H24N4O4 |
| Molecular Weight | 504.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Tadalafil Impurity 77 (C30H24N4O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 21.0, corresponding to approximately 21 ring(s) or double-bond equivalent(s). With a molecular weight of 504.54 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Tadalafil Impurity 77 (CAS 2064212-00-4, C30H24N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tadalafil Impurity 77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H24N4O4 |
| Molecular Weight | 504.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 4 |
Related Tadalafil Standards
- Tadalafil Impurity 151 (CAS 2520114-64-9)
- Tadalafil Impurity 68 (CAS CATO-C4X-108768)
- Tadalafil Impurity 69 (CAS CATO-C4X-108769)
- Tadalafil Impurity 51 (CAS CATO-C4X-108751)
- Tadalafil Impurity 150 (CAS 2361527-35-5)
- Tadalafil Impurity 108 (CAS CATO-C4X-1087108)
- Tadalafil Impurity 168 (CAS CATO-C4X-1087168)
- Tadalafil Impurity 109 (CAS CATO-C4X-1087109)
Recommended Standards
- Palbociclib Impurity 198 (CAS CATO-C4X-1125198)
- Lenalidomide-PEG4-C2-azide (CAS 2399455-55-9)
- Cefamandole EP Impurity C (CAS 36922-15-3)
- PAd-DalPhos (CAS 1902911-38-9)
- Levofloxacin Impurity 101 (CAS 105804-40-8)
- Doxylamine EP Impurity D (CAS 91-02-1)
- Ozenoxacin Impurity 58 (CAS CATO-C4X-279658)
- 1-Butanol, 2-[[9-(1-methylethyl)-6-[[[4-(2-pyridinyl)phenyl]methyl]amino]-9H-purin-2-yl]amino]-, (2R)- 294646-77-8 (CAS 294646-77-8)
- Di-m-tolylmethanol (CAS 13389-72-5)
- N-benzyl-1,2,5-thiadiazole-3-carboxamide (CAS 709000-51-1)
- 5-Ethyl-1-(3-methylbutyl)-1h-pyrazole-4-carboxylic acid (CAS 1247986-13-5)
- (7-Fluoro-2,3-dihydrobenzofuran-2-yl)methanamine (CAS 872517-40-3)
- (3R,5S)-3-ethynyl-3-hydroxy-1,5-dimethyl-pyrrolidin-2-one (CAS 2561460-98-6)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com