2-(3-Fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine CAS 372122-53-7
| CAS No. | 372122-53-7 |
| Molecular Formula | C14H8F4N2 |
| Molecular Weight | 280.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3-Fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine (CAS 372122-53-7) is a high-purity analytical reference standard with the molecular formula C14H8F4N2 and a molecular weight of 280.22 g/mol.
The molecular framework of 2-(3-Fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine (C14H8F4N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(3-Fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F4N2 |
| Molecular Weight | 280.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 2-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1196131-36-8)
- 2-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1420885-96-6)
- 2-(4-Fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine (CAS 372122-55-9)
- 2-{3-[(2-fluorophenyl)methyl]-2,4,5-trioxoimidazolidin-1-yl}acetic acid (CAS 303986-57-4)
- 5-(2-(4-Fluorophenyl)acetyl)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 1174047-11-0)
- (4-Fluorophenyl)diphenylphosphane (CAS 18437-72-4)
- 4-(4-(4-Fluorophenyl)piperazin-1-yl)-4-oxobutanoic acid (CAS 354551-55-6)
- 8-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]decane-8-carboxylic acid (CAS 56327-03-8)
Recommended Standards
- ML318 (CAS 1610516-67-0)
- 3-((2,2,3,3-Tetrafluoropropoxy)methyl)benzohydrazide (CAS 438473-63-3)
- 4-((2,2,3,3-Tetrafluoropropoxy)methyl)benzohydrazide (CAS 438473-25-7)
- 5-(3-(Trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (CAS 75175-84-7)
- Tos-Gly-OSu (CAS 68385-26-2)
- 7-O-w-Bromopropyldaidzein (CAS 309252-38-8)
- 1-(Furan-2-yl)-2-methylpropan-1-one (CAS 4208-53-1)
- 2-[1-(3-Fluorophenyl)-1H-pyrazole-4-carbonyl]phenol (CAS 956624-10-5)
- 2-Cyano-1-benzothiophene-3-sulfonyl chloride (CAS 1334626-84-4)
- 2-((4-(Tert-butyl)benzyl)thio)-6,7-dimethoxy-3-(4-methoxybenzyl)quinazolin-4(3H)-imine (CAS 439096-26-1)
- Ethyl 2-Chloro-2-nitroacetate (CAS 14011-27-9)
- Tert-butyl 3-[4-(methoxycarbonyl)phenyl]piperazine-1-carboxylate (CAS 1380861-63-1)
- (3-Aminopropyl)(difluoromethyl)phosphinic acid (CAS 133345-73-0)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
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