3-Chloro-2-methyl-N-(4-(2-(3-oxomorpholino)ethyl)thiazol-2-yl)benzenesulfonamide CAS 376641-49-5
| CAS No. | 376641-49-5 |
| Molecular Formula | C16H18ClN3O4S2 |
| Molecular Weight | 415.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Chloro-2-methyl-N-(4-(2-(3-oxomorpholino)ethyl)thiazol-2-yl)benzenesulfonamide (CAS 376641-49-5), molecular formula C16H18ClN3O4S2 and molecular weight 415.91 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chloro-2-methyl-N-(4-(2-(3-oxomorpholino)ethyl)thiazol-2-yl)benzenesulfonamide (C16H18ClN3O4S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18ClN3O4S2 |
| Molecular Weight | 415.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- 2-(1-(1-Benzhydrylazetidin-3-yl)-1H-pyrazol-5-yl)-4-chlorophenol, 97% (CAS 1235406-99-1)
- N-(2-((4-chlorophenyl)sulfonyl)ethyl)-2-(phenylsulfonyl)propanamide (CAS 860609-54-7)
- ((4-(2-Chlorophenoxy)phenyl)sulfonyl)methionine (CAS 1009715-74-5)
- N-(2-((4-chlorophenyl)sulfonyl)ethyl)-3-(phenylsulfonyl)propanamide (CAS 337923-29-2)
- 1-(6-Methylpyridin-2-yl)-N'-[(1E)-phenylmethylidene]-1H-imidazole-4-carbohydrazide (CAS 478257-55-5)
- Bicyclo[2.2.2]octane-1,4-diylbis(diphenylphosphineoxide) (CAS 114378-29-9)
- 4,4'-Diiodo-1,1'-binaphthalene (CAS 62012-57-1)
- (S)-2-Amino-1-((R)-3-((cyclopropylmethyl)amino)piperidin-1-yl)propan-1-one (CAS 1401668-34-5)
- DL-Methyl benzylvalinate (CAS 219946-45-9)
- Methyl 4-(trifluoromethyl)furan-2-carboxylate (CAS 1216095-28-1)
- Fluralaner Impurity 50 (CAS 1309959-46-3)
- 3-(4-((2-Aminoethyl)amino)-1,2,5-oxadiazol-3-yl)-4-(3-bromo-4-fluorophenyl)-1,2,4-oxadiazol-5(4H)-one hydrochloride (CAS 1204669-67-9)
- 3-Bromo-5-methyl-2-nitroaniline (CAS 1807224-86-7)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
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