Amoxicillin Impurity 28 CAS 37727-80-3
| CAS No. | 37727-80-3 |
| Molecular Formula | C8H14N2O4S |
| Molecular Weight | 234.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Amoxicillin Impurity 28 (CAS 37727-80-3, C8H14N2O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Amoxicillin Impurity 28 (C8H14N2O4S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Amoxicillin Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H14N2O4S |
| Molecular Weight | 234.27 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amoxicillin Standards
- Amoxicillin Impurity 85(Mixture) (CAS CATO-C4X-114885)
- Amoxicillin Impurity 107 (CAS CATO-C4X-1148107)
- rac-Amoxicillin EP Impurity H (CAS 106644-43-3)
- Amoxicillin EP Impurity H (CAS 205826-86-4)
- Amoxicillin EP Impurity A(Sulbactam EP Impurity B) (CAS 551-16-6)
- Amoxicillin Impurity 100 (CAS CATO-C4X-1148100)
- Amoxicillin Impurity 41 (CAS CATO-C4X-114841)
- Amoxicillin Impurity 93 (CAS CATO-C4X-114893)
Recommended Standards
- Vonoprazan Impurity 298 (CAS 103860-56-6)
- 3623AE 438229-64-2 C11H10N2O2S Methyl 2-amino-4-pyridin-4-ylthiophene-3-carboxylate (CAS 438229-64-2)
- Fosfomycin Impurity 38 (CAS 25383-05-5)
- α-Methyl-D,L-tryptophan-1-14C Methyl EsterDISCONTINUED (CAS 210357-35-0)
- Ropinirole EP Impurity E (CAS CATO-C4X-174511)
- Eltrombopag Impurity 32 (CAS 98775-19-0)
- Rosuvastatin Impurity 217 (CAS CATO-C4X-1169217)
- 2-(4-Methoxyphenethyl)-4H-chromen-4-one (CAS 92911-82-5)
- Ibrutinib Impurity 111 (CAS CATO-C4X-1064111)
- 1-(5-Bromo-3-fluoro-2-nitrophenyl)ethan-1-one (CAS 1805555-86-5)
- 8-Bromo-1,7-naphthyridine (CAS 63845-72-7)
- 3-Amino-2-(pyridin-4-yl)quinazolin-4(3H)-one (CAS 310437-08-2)
- Rac-dimethylsilylbis(2-methyl-indenyl)zirconium(IV)dichloride (CAS 182210-68-0)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com