Methyl 2-bromo-2,3,3,3-tetrafluoropropanoate CAS 378-67-6
| CAS No. | 378-67-6 |
| Molecular Formula | C4H3BrF4O2 |
| Molecular Weight | 238.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 238.96 g/mol gives Methyl 2-bromo-2,3,3,3-tetrafluoropropanoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 2-bromo-2,3,3,3-tetrafluoropropanoate (CAS 378-67-6) is a high-purity analytical reference standard with the molecular formula C4H3BrF4O2 and a molecular weight of 238.96 g/mol.
Methyl 2-bromo-2,3,3,3-tetrafluoropropanoate (C4H3BrF4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 2-bromo-2,3,3,3-tetrafluoropropanoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H3BrF4O2 |
| Molecular Weight | 238.96 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
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Recommended Standards
- (2-(bromomethyl)-4-fluorophenyl)boronic acid (CAS 850568-01-3)
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- 2-Iodo-5-nitro-1H-imidazole (CAS 13369-81-8)
- Trt-Met-OH . DEA (E-3525.0025) (CAS 80514-69-8)
- 3-Amino-2-(3,4,5-trimethoxybenzyl)propanoic acid (CAS 1260592-11-7)
- 4-(2-Isopropoxypropan-2-yl)thiazol-2-amine (CAS 2293131-41-4)
- Pentabromodiphenylether (technical) (CAS 32534-81-9)
- 2-(Naphthalen-2-yl)isonicotinic acid (CAS 100004-92-0)
- Decanoyl-Arg-Val-Arg-Lys-chloromethylketone (CAS 534615-50-4)
- Dodecyl Hydrogen Fumarate (CAS 10283-72-4)
- 1-Benzhydryl-3-(5-(thiophen-3-yl)-1,3,4-oxadiazol-2-yl)urea (CAS 1251686-95-9)
- Silodosin impurity 22 (CAS CATO-C4X-175422)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
Why CATO?
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