tert-Butyl 3-(benzyloxy)benzoate CAS 378787-46-3
| CAS No. | 378787-46-3 |
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 284.35 g/mol gives tert-Butyl 3-(benzyloxy)benzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
tert-Butyl 3-(benzyloxy)benzoate (CAS 378787-46-3) is a high-purity analytical reference standard with the molecular formula C18H20O3 and a molecular weight of 284.35 g/mol.
Structurally, tert-Butyl 3-(benzyloxy)benzoate (C18H20O3) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 284.35 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Recommended Standards
- tert-Butyl 3-(aminomethyl)-1-oxo-2-oxa-8-azaspiro[4.5]decane-8-carboxylate (CAS 2126161-13-3)
- Tert-butyl 4-(3-cyanophenyl)-3,6-dihydropyridine-1(2H)-carboxylate (CAS 370864-42-9)
- tert-butyl 3-(4-amino-3-methylpyridin-2-yl)benzoate (CAS 2436676-17-2)
- tert-Butyl 4-(benzyloxy)benzoate (CAS 312631-23-5)
- 5-Chloro-1-(4-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 339024-25-8)
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