5-(3-(4-Fluorophenyl)ureido)-N,N,2-trimethylbenzenesulfonamide CAS 380320-85-4
| CAS No. | 380320-85-4 |
| Molecular Formula | C16H18FN3O3S |
| Molecular Weight | 351.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(3-(4-Fluorophenyl)ureido)-N,N,2-trimethylbenzenesulfonamide.
5-(3-(4-Fluorophenyl)ureido)-N,N,2-trimethylbenzenesulfonamide (CAS 380320-85-4) is a high-purity analytical reference standard with the molecular formula C16H18FN3O3S and a molecular weight of 351.40 g/mol.
The molecular framework of 5-(3-(4-Fluorophenyl)ureido)-N,N,2-trimethylbenzenesulfonamide (C16H18FN3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(3-(4-Fluorophenyl)ureido)-N,N,2-trimethylbenzenesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H18FN3O3S |
| Molecular Weight | 351.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 3-(4-Fluorophenyl)-5-((4-(p-tolyl)thiazol-2-yl)methyl)-1,2,4-oxadiazole (CAS 1112280-09-7)
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- (4-(4-Fluorophenyl)-1H-pyrrol-2-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone (CAS 1219845-17-6)
- 7-(4-Fluorophenyl)-2-(methylsulfonyl)thieno[3,2-d]pyrimidine-6-carboxamide (CAS 1462949-98-9)
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Recommended Standards
- 4-[2-(2-Methoxyethoxy)ethoxy]-6-(pyridin-2-yl)-2,2'-bipyridine (CAS 613665-49-9)
- 5-(Dimethylamino)-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-2,3-dihydropyridazin-3-one (CAS 551921-39-2)
- 4-(Acridin-9-yl)-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one (CAS 90878-34-5)
- 5-Amino-N-(3-methoxybenzyl)-1-(2-methylbenzyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899981-97-6)
- (4aR,7aS)-rel-Hexahydro-2H-[1,4]dioxino[2,3-c]pyrrole Hydrochloride (CAS 694439-04-8)
- 1-((1-Methylcyclopropyl)sulfonyl)-3-((triethylsilyl)oxy)azetidine (CAS 1187594-24-6)
- 1-(3-Methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1082367-21-2)
- 6-(Perfluoropropyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 88191-88-2)
- Methyl 3-(4-aminobenzenesulfonamido)propanoate hydrochloride (CAS 1052546-14-1)
- Harman-d3 (CAS 1216708-84-7)
- Famotidine Impurity 27 (CAS 1378820-83-7)
- 2,5-Dioxopyrrolidin-1-yl 2,4-dimethoxybenzoate (CAS 1638612-98-2)
- N,N-dimethyl-1-(piperidin-4-yl)-1H-pyrazol-4-amine dihydrochloride (CAS 1820684-17-0)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
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