Famotidine Impurity 27 CAS 1378820-83-7
| CAS No. | 1378820-83-7 |
| Molecular Formula | C5H7ClN4S |
| Molecular Weight | 190.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 190.65 g/mol gives Famotidine Impurity 27 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Famotidine Impurity 27 (CAS 1378820-83-7) is a certified pharmaceutical impurity reference standard with the molecular formula C5H7ClN4S and a molecular weight of 190.65 g/mol.
Famotidine Impurity 27 (C5H7ClN4S) contains a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Famotidine Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H7ClN4S |
| Molecular Weight | 190.65 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Famotidine Standards
- Famotidine Impurity 02 (CAS 81152-53-6)
- Famotidine Impurity 39 (CAS CATO-C4X-139239)
- Famotidine Impurity 82 (CAS CATO-C4X-139282)
- Famotidine Impurity 50 (CAS 95853-51-3)
- Famotidine Impurity 78 (CAS 88068-99-9)
- Famotidine Impurity 79 (CAS CATO-C4X-139279)
- Famotidine Impurity 45 (CAS 1644079-90-2)
- Famotidine Impurity 54 (CAS CATO-C4X-139254)
Recommended Standards
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- Clodronic Acid Disodium Salt (CAS 22560-50-5)
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- 1-(3-(4-Iodophenoxy)propyl)-2-methylpyrrolidine (CAS 935745-06-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com