2-Hydroxy-2-methyl-3-[3-(trifluoromethyl)benzenesulfonyl]-N-[4-(trifluoromethyl)phenyl]propanamide CAS 338956-14-2
| CAS No. | 338956-14-2 |
| Molecular Formula | C18H15F6NO4S |
| Molecular Weight | 455.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 455.37 g/mol gives 2-Hydroxy-2-methyl-3-[3-(trifluoromethyl)benzenesulfonyl]-N-[4-(trifluoromethyl)phenyl]propanamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Hydroxy-2-methyl-3-[3-(trifluoromethyl)benzenesulfonyl]-N-[4-(trifluoromethyl)phenyl]propanamide (CAS 338956-14-2), molecular formula C18H15F6NO4S and molecular weight 455.37 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Hydroxy-2-methyl-3-[3-(trifluoromethyl)benzenesulfonyl]-N-[4-(trifluoromethyl)phenyl]propanamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 455.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Hydroxy-2-methyl-3-[3-(trifluoromethyl)benzenesulfonyl]-N-[4-(trifluoromethyl)phenyl]propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15F6NO4S |
| Molecular Weight | 455.37 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Hydroxy Standards
- 2-Hydroxy-2-methyl-3-[3-(trifluoromethyl)benzenesulfonyl]-N-[3-(trifluoromethyl)phenyl]propanamide (CAS 339275-77-3)
- 2-Hydroxy-2-(naphthalen-1-yl)acetic acid (CAS 6341-54-4)
- 6-Hydroxy-5-((5-methoxy-1-(phenylsulfonyl)-1H-indol-3-yl)methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (CAS 1185163-68-1)
- (4-Hydroxy-4-(((2-methylbenzyl)sulfonyl)methyl)piperidin-1-yl)(3-(trifluoromethyl)phenyl)methanone (CAS 866019-52-5)
- (2S)-1-[[2-Hydroxy-3-(trifluoromethyl)phenyl]methyl]-α,α-bis(4-methylphenyl)-2-pyrrolidinemethanol (CAS 1429648-15-6)
- (S)-3-Hydroxy-2-methoxy-5-((2-(trimethylsilyl)ethoxy)methyl)-7,12-dihydrobenzo[5,6][1,4]diazepino[1,2-b]isoquinoline-6,14(5H,6aH)-dione (CAS 1964489-90-4)
- α-Hydroxy-3,4-bis(phenylmethoxy)benzeneacetic Acid Phenylmethyl Ester (CAS 113026-97-4)
- 2-Hydroxy-2’-(diphenylphosphino)-1,1’-binaphthalene (CAS 199796-91-3)
Recommended Standards
- 5-Fluoro-1-(4-fluorobenzyl)pyrimidine-2,4(1H,3H)-dione (CAS 86547-17-3)
- 2-Bromo-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)hexanamide (CAS 380467-37-8)
- Crizotinib-d5 (CAS 1395950-84-1)
- 1, 4-PREGNADIEN-9α, 11β-DICHLORO-17, 21-DIOL-3, 20-DIONE 21-ACETATE (CAS 79-61-8)
- Favipiravir Impurity 23 (CAS 356783-14-7)
- 5-Propylcyclohexane-1,3-dione (CAS 57641-89-1)
- 5-Chloro-1H-pyrazole hydrochloride (CAS 1881293-85-1)
- 7-Chlorodioxindole (CAS 99304-29-7)
- 1,5-Dinitroanthracene-9,10-dione (CAS 82-35-9)
- 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl chloride (CAS 25320-59-6)
- 1-(Chloromethyl)-8-iodonaphthalene (CAS 1072102-34-1)
- 5,7-Bis(benzyloxy)-2-(4-(benzyloxy)phenyl)-4H-chromen-4-one (CAS 96333-59-4)
- 2-Amino-N-cyclopropyl-N-((S)-1-phenylpropyl)propanamide (CAS 1354028-56-0)
- Des-Val23-Tirzepatide (CAS CATO-CPTD788950)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com