Inosine impurity 3 CAS 38183-47-0
| CAS No. | 38183-47-0 |
| Molecular Formula | C10H12N4O5 |
| Molecular Weight | 268.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Inosine impurity 3 (CAS 38183-47-0, C10H12N4O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Inosine impurity 3 (C10H12N4O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12N4O5 |
| Molecular Weight | 268.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 4 |
Related Inosine Standards
Recommended Standards
- Vidarabine Impurity 1 (CAS 7013-16-3)
- 3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1018170-82-5)
- 1,4-Dihydro-4-|A-D-ribofuranosyl-5H-1,2,3-triazolo[4,5-b]pyridin-5-one 4-(|A-D-Ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one 59892-40-9 (CAS 59892-40-9)
- 1-(3-Fluoro-2-nitrophenyl)piperidine-4-carboxylic acid (CAS 1179098-08-8)
- Atrasentan Impurity 63 (CAS 1140456-19-4)
- Ritonavir Impurity 59 (CAS CATO-C4X-175159)
- Amorolfine Impurity 63 (CAS CATO-C4X-154263)
- Mesosulfuron Impurity 3 (CAS 393509-80-3)
- 3,5-Dichloro-4-mercaptophenol (CAS 1803611-46-2)
- Methyl 2-(1-(4-iodophenyl)-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl)acetate (CAS 1355227-40-5)
- 2-Chloro-4,5-difluoropyrimidine (CAS 894791-89-0)
- 4-Bromo-5,7-difluoro-2-propylquinoline (CAS 1189106-83-9)
- 2-Oxo-2-(2-phenylindolizin-3-yl)acetic acid (CAS 892691-05-3)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com