Flumetasone Impurity 10 CAS 382631-11-0
| CAS No. | 382631-11-0 |
| Molecular Formula | C21H26ClFO5 |
| Molecular Weight | 412.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Flumetasone Impurity 10 (CAS 382631-11-0, C21H26ClFO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H26ClFO5, Flumetasone Impurity 10 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 412.88 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Flumetasone Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H26ClFO5 |
| Molecular Weight | 412.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Flumetasone Standards
- Flumetasone Impurity 19 (CAS CATO-C4X-191019)
- Flumetasone Impurity 15 (CAS CATO-C4X-191015)
- Flumetasone Impurity 17 (CAS CATO-C4X-191017)
- Flumetasone Impurity 16 (CAS CATO-C4X-191016)
- Flumetasone Impurity 18 (CAS CATO-C4X-191018)
- Flumetasone Impurity 9 (CAS 2541-37-9)
- Flumetasone Impurity 14 (CAS 3873-19-6)
- Flumetasone Impurity 7 (CAS 61633-73-6)
Recommended Standards
- 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-N,N-diethylthiophene-2-sulfonamide (CAS 344278-38-2)
- 2-((1S,4S)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)acetaldehyde (CAS 656810-85-4)
- Halcinonide Impurity N2 (CAS 982-91-2)
- Pyraoxystrobin (CAS 862588-11-2)
- Lornoxicam Impurity 45 (CAS CATO-C4X-201645)
- Aztreonam Impurity 23 (CAS CATO-C4X-152223)
- Cefmetazole Impurity 5 (CAS CATO-C4X-15075)
- 3,3-Dibromo-2-oxopropanoic acid (CAS 600-35-1)
- Phenyl N-iso-Propyl-d7-carbamate (CAS 1329835-22-4)
- 4-Azetidinomethyl-3-methoxybenzophenone (CAS 898777-37-2)
- 2-Chloro-4-(tetrahydro-2H-pyran-4-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 2387185-13-7)
- N-(tert-butyl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide (CAS 1050824-22-0)
- N-(2-Methoxyethyl)-2-(3-oxodecahydroquinoxalin-2-yl)acetamide (CAS 1428139-03-0)
- Hexapeptide-9 (CAS 1228371-11-6)
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