Flumetasone Impurity 19 CAS CATO-C4X-191019
| CAS No. | CATO-C4X-191019 |
| Molecular Formula | C21H26ClFO5 |
| Molecular Weight | 412.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Flumetasone Impurity 19 (CAS CATO-C4X-191019, C21H26ClFO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Flumetasone Impurity 19 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 412.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Flumetasone Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H26ClFO5 |
| Molecular Weight | 412.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Flumetasone Standards
- Flumetasone Impurity 10 (CAS 382631-11-0)
- Flumetasone Impurity 15 (CAS CATO-C4X-191015)
- Flumetasone Impurity 17 (CAS CATO-C4X-191017)
- Flumetasone Impurity 16 (CAS CATO-C4X-191016)
- Flumetasone Impurity 18 (CAS CATO-C4X-191018)
- Flumetasone Impurity 9 (CAS 2541-37-9)
- Flumetasone Impurity 14 (CAS 3873-19-6)
- Flumetasone Impurity 7 (CAS 61633-73-6)
Recommended Standards
- Halcinonide Impurity N2 (CAS 982-91-2)
- 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-N,N-diethylthiophene-2-sulfonamide (CAS 344278-38-2)
- 2-(((3-(3-Chlorophenyl)-1,2,4-oxadiazol-5-yl)methyl)thio)-3-isopropylquinazolin-4(3H)-one (CAS 919958-83-1)
- 2-((1S,4S)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)acetaldehyde (CAS 656810-85-4)
- Isosulfan Blue impurity 9 (CAS CATO-C4X-30459)
- Piracetam Impurity 20 (CAS 94359-90-7)
- Ammoxetine Impurity 1 (CAS CATO-C4X-33571)
- (E)-1-(4-chlorophenyl)-3-[5-(2,4-dichlorophenyl)-2-furyl]-2-propen-1-one 338777-15-4 KS-00001XQM (CAS 338777-15-4)
- 4-Chloro-5-methoxybenzo[d]thiazol-2-amine (CAS 736894-42-1)
- Methyl 4,5-diaminothiophene-2-carboxylate (CAS 106850-18-4)
- Methyl 4-iodo-1H-indazole-6-carboxylate (CAS 885519-33-5)
- 4-(1-Bromoethyl)-2-chloro-1-methoxybenzene (CAS 191092-37-2)
- (S)-2-((tert-Butoxycarbonyl)amino)-2-(3-(trifluoromethyl)phenyl)acetic acid (CAS 1035490-76-6)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
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