去甲肾上腺素杂质1盐酸盐 CAS 3868-81-3
| CAS No. | 3868-81-3 |
| Molecular Formula | C12H19NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 去甲肾上腺素杂质1盐酸盐 (CAS 3868-81-3), a pharmacopoeial impurity reference standard (molecular formula C12H19NO3HCl, MW 261.75 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of 去甲肾上腺素杂质1盐酸盐 (C12H19NO3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), 去甲肾上腺素杂质1盐酸盐 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H19NO3 HCl |
| Molecular Weight | 261.75 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Omadacycline Impurity 28 (CAS CATO-C4X-285728)
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- {[4-(bromomethyl)phenyl]methoxy}(tert-butyl)dimethylsilane (CAS 125320-20-9)
- 1-(3-Bromophenyl)-1,3-dihydro-2H-imidazol-2-one (CAS 944709-54-0)
- Trans-2-vinylcyclopropane-1-carboxylic acid (CAS 2183-88-2)
- 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1-(m-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618383-05-4)
- 7-Methoxy-2,3-dihydrobenzo[b][1,4]dioxin-6-amine (CAS 76958-06-0)
- Peptide Impurity 04 (CAS 2913424-91-4)
Why CATO?
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